MOGAD is a rare condition that affects the central nervous system. The aim of this study is to test how effective and safe satralizumab is for treating adults and teenagers with MOGAD. The METEOROID study will look to see if satralizumab is safe and whether it works as treatment for MOGAD – for both preventing attacks and improving symptoms.
Recruitment
Aged >12 years
Diagnosis of MOG antibody disease
Documented history of ≥2 MOGAD attacks
Stable disease for 12 weeks before first dose
No present or recurrent bacterial, viral, fungal, or other infection (excluding fungal infection of nail beds or dental caries)
Able to tolerate MRI
No history of cancer or other significant medical conditions